Mucocutaneous Side Effects of Antineoplastic Drugs Used in Cancer Therapy in Erbil

June 2019 in “ Advanced medical journal ”

Niyan Othman Hama Faraj, Mohammed Yousif Saeed

anagen effluvium hair changes skin changes nail changes mucosal changes aphthous ulcers

TLDR Cancer drugs often cause temporary hair, skin, nail, and mouth issues.

The study conducted on 109 cancer patients in Erbil aimed to identify common mucocutaneous side effects of antineoplastic drugs. The majority of patients (87 females and 22 males) experienced hair changes (31.71%), with anagen effluvium being the most prevalent. Skin changes were observed in 28.29% of patients, nail changes in 20.49%, and mucosal changes in 19.51%, with aphthous ulcers being common. The study concluded that while these adverse effects caused significant morbidity, most complications subsided after cessation of therapy without permanent damage.

View this study on amj.khcms.edu.krd →

Discuss this study in the Community →

Related Community Posts Join

6 / 266 results

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 1 year ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community Fin shed is no joke. This is from running my hand through my hair on my way home

in Finasteride/Dutasteride 1053 upvotes 2 months ago

The conversation is about hair shedding experienced while using finasteride (fin) for hair loss treatment. Users discuss their experiences with finasteride, minoxidil (min), and other treatments, noting that shedding is often a sign that the treatment is working.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community I destroyed my scalp so you wouldn't have to: here's what happens when you quit topical minoxidil

in Minoxidil 280 upvotes 1 year ago

Quitting minoxidil can lead to significant hair loss, even in areas that were not thinning before, as hair becomes reliant on the treatment. Some users also report losing hair gains when stopping minoxidil despite taking finasteride.

community Does anyone here use everything except Fin

in Minoxidil 23 upvotes 1 year ago

The conversation is about hair loss treatments, specifically Minoxidil (Min) and Finasteride (Fin). The original poster is considering using Min and other treatments but is hesitant about Fin, while the responses vary, with some advocating for early use of Fin and others warning about potential side effects.

Related Research

4 / 4 results

research Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review

1 citations, August 2021 in “Cosmoderma”

Low-dose oral minoxidil is effective and well-tolerated for treating hair loss.

research Mucocutaneous Side Effects of Antineoplastic Drugs Used in Cancer Therapy in Erbil

June 2019 in “Advanced medical journal”

Cancer drugs often cause temporary hair, skin, nail, and mouth issues.

research A Split Head Study of Efficacy of Placebo Versus Platelet-Rich Plasma Injections in the Treatment of Androgenic Alopecia

33 citations, January 2017 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.

research Expanding Research and Development of Novel Agents for the Treatment and Prevention of Chemotherapy-Induced Alopecia

1 citations, May 2006 in “Expert Opinion on Therapeutic Patents”

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.