Impact of Different Mating and Surgical Protocols on the Establishment of a Mouse Model for Fetal Scarless Skin Healing

    September 2025 in “ Biological Procedures Online ”
    Lu Huang, Xinran Ye, Yifan Zhang … Qingfeng Li
    Studysummary This study presented a refined surgical protocol for a fetal mouse model that improves pregnancy success, reduces fetal loss, and allows for consistent phenotypic outcomes, enhancing research in scarless skin regeneration.
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    Research cited in this study 6

    1. Actin cable formation and epidermis–dermis positional relationship during complete skin regeneration Scientific Reports · 2022
    2. An In Vivo Mouse Excisional Wound Model of Scarless Healing Plastic and Reconstructive Surgery · 2006
    3. Mammalian Fetal Organ Regeneration Advances in Biochemical Engineering / Biotechnology · 2005
    4. Confocal Microscopic Analysis of Scarless Repair in the Fetal Rat Plastic & Reconstructive Surgery · 2002
    5. Differential Expression of Fibromodulin, a Transforming Growth Factor-Beta Modulator, in Fetal Skin Development and Scarless Repair American Journal of Pathology · 2000
    6. Animal Models for the Study of Fetal Tissue Repair Journal of Surgical Research · 1991