Metabolic Syndrome in Alopecia Areata: An Observational Study at a Tertiary Care Center

August 2021 in “ International Journal of Research in Dermatology ”

Subrata K. Das, Saptadipa Das

TLDR There is no significant link between metabolic syndrome and alopecia areata.

This study aimed to evaluate the parameters of metabolic syndrome (MS) in patients with alopecia areata (AA) and investigate any potential relationship between the two. Conducted at a tertiary care center, the cross-sectional observational study included 50 patients with AA, predominantly in the age group of 20-30 years. The study found that most patients had mild AA, with no significant derangement of clinical and laboratory parameters of MS observed in these patients. Thus, the study concluded that there was no significant relationship between MS and AA in the observed cohort.

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research Metabolic Syndrome in Alopecia Areata: An Observational Study at a Tertiary Care Center

1 citations , August 2021 in “International Journal of Research in Dermatology”

There is no significant link between metabolic syndrome and alopecia areata.

research Association Between Alopecia Areata, Psoriasis Vulgaris, Thyroid Disease, And Metabolic Syndrome

17 citations , December 2013 in “Journal of Investigative Dermatology Symposium Proceedings”

Autoimmune and metabolic issues are linked, and treating one may worsen another.

research The Association of Insulin Resistance and Metabolic Syndrome in Early Androgenetic Alopecia

18 citations , December 2010 in “PubMed”

People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.

research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle

185 citations , August 2005 in “Autoimmunity Reviews”

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

275 citations , November 2002 in “International Journal of Dermatology”

Alopecia areata mainly affects young people and has significant psychological impacts, especially in males.

research Decreased Lymphocyte Reactivity and Autoimmunity in Alopecia Areata

54 citations , August 1981 in “British Journal of Dermatology”

Alopecia areata is linked to reduced T cell function and auto-immunity.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

in Research/Science 44 upvotes 11 months ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community When are we getting a cure to hair loss?

in Chat 2 years ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 1 year ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

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A child with rough nails also had hair loss and allergies.