The Mechanism of Action of Platelet-Rich Plasma – Composition Analysis and Safety Assessment

December 2021 in “ Current Issues in Pharmacy and Medical Sciences ”

Anna Maria Lichtarska, Malgorzata Maria Sokol

platelet-rich plasma PRP growth factors skin regeneration biostimulation buffy coat angiogenesis cell differentiation cell proliferation cell synthesis

TLDR Platelet-rich plasma therapy is effective and safe for skin regeneration and anti-aging.

The document discusses the use of platelet-rich plasma (PRP) therapy in aesthetic medicine, particularly for anti-aging treatment. PRP therapy uses the patient's own cells, with growth factors playing a crucial role in skin regeneration and biostimulation. The procedure involves the collection and administration of a buffy coat to the patient, and when performed correctly, it yields positive results. The therapy is proven to be effective and safe, as supported by numerous studies. The concentrated platelets in the PRP stimulate surrounding cells to angiogenesis, differentiation, proliferation, and synthesis of essential components for remodeling the treated area.

View this study on sciendo.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 79 results

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What else is good. Besides the big 3.

in Chat 34 upvotes 2 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 55 upvotes 1 month ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community How can I get fin in Canada (GP and Derm turned me down) + questions on minoxidil and PRP

7 upvotes 6 years ago

Treatments for hair loss with a focus on finasteride, minoxidil, and platelet-rich plasma (PRP). The user discussed their family history of balding, asked questions about the effectiveness of different treatments, and was discouraged from taking finasteride by medical professionals.

community I have successfully stopped my hormone-induced hair loss ( caused by PCOS,) for 2 years now but I can't seem to be able to regrow the lost hair. Has anyone tried Platelet-Rich Plasma Therapy (PRP)?

in Female 6 upvotes 3 years ago

GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.

Related Research

1 / 1 results

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations, November 2017 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.