The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

January 2009 in “ The Year book of dermatology ”

B.H. Thiers

Ludwig pattern androgenetic alopecia androgen sensitivity follicular units miniaturization terminal hairs vellus hairs hair follicles female pattern hair loss AGA hair thinning hair miniaturization

TLDR Ludwig pattern hair loss results from varying androgen sensitivity, causing fewer thick hairs and more thin hairs.

The Ludwig pattern of androgenetic alopecia is caused by a hierarchy of androgen sensitivity within follicular units, leading to selective miniaturization and a reduction in the number of terminal hairs per follicular unit. Women with androgenetic alopecia have fewer terminal hairs per follicular unit and an increase in the number of vellus hairs, but complete miniaturization of all hairs within the follicular unit is not seen. This supports the hypothesis of a hierarchy of susceptibility within follicular units to androgenetic alopecia. Further investigation is required to ascertain whether secondary and tertiary hair follicles are more susceptible than primary follicles.

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The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

47 citations, September 2008 in “British Journal of Dermatology”

Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.

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community Diffuse hair loss and scalp biopsies

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

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The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community Androgenetic alopecia - I want your honest opinion

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A female user's diagnosis of androgenetic alopecia, and the advice shared in response which suggests taking spironolactone and minoxidil together to prevent hair loss.

community AGA evaluation and first steps - BEGINNER MEGAPOST

in Chat 76 upvotes 3 months ago

The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.

community Would you still need to be on finasteride if Verteporfin becomes widely used?

in Research/Science 25 upvotes 1 year ago

The conversation discusses whether finasteride would still be necessary if Verteporfin becomes a successful hair loss treatment. It also explores the sensitivity of transplanted hair to DHT and the potential for off-label use of Verteporfin post hair transplant.

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in Research/Science 149 upvotes 1 month ago

Diffuse thinning is worse than a receding hairline as it affects the entire scalp, complicating styling and hair transplants. Treatments like finasteride, minoxidil, dutasteride, and RU58841 are mentioned, with some users noting improved hair density.

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