Lichen Sclerosus Et Atrophicus And Autoimmunity In 250 Women

    July 1985 in “ British journal of dermatology/British journal of dermatology, Supplement ”
    Rhian Thomas, C. M. Ridley, David McGibbon, Martin Black
    TLDR Autoimmune-related phenomena do not affect the progression or characteristics of lichen sclerosus in women.
    In a study conducted 38 years ago on the relationship between lichen sclerosus et atrophicus (LSA) and autoimmunity, 250 women with histologically confirmed LSA were examined. The study found that 52 women (20.8%) had a personal history of autoimmune-related diseases, 55 women (22%) had a family history of such diseases, and 109 women (43.6%) had one or more autoantibodies in a titre of 1:20 or greater. Despite these findings, the study concluded that there were no significant differences in the natural history of LSA between patients with autoimmune-related phenomena and those without. This included factors such as the duration of LSA, age at onset, relationship to puberty or menopause, sites of involvement, and malignant change in LSA-affected skin. The study suggested that the presence of autoimmune-related phenomena does not influence the progression or characteristics of LSA.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 59 results

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 4 weeks ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 7 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Making the jump to hair systems

      in Hair Systems  26 upvotes 3 years ago
      19-year-old with Lichen Planopilaris tried various treatments unsuccessfully. Now considering hair systems, seeking experiences and opinions.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  99 upvotes 1 month ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Anger and frustration as I finally learn my diagnosis.

      in Female  6 upvotes 1 year ago
      A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

    Related Research

    1 / 1 results