Label-Free Automated Cell Tracking: Analysis of the Role of E-Cadherin Expression in Collective Electrotaxis

    Mark L. Lalli, Brooke Wojeski, Anand R. Asthagiri
    Studysummary This study demonstrated that an automated algorithm can effectively track epithelial cell movement within clusters, revealing that partial knockdown of E-cadherin reduces electrotactic potential in breast epithelial cells, particularly in free-moving clusters, and suggesting an adhesion-independent role of E-cadherin in regulating cell electrotaxis.
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