14 citations
,
June 2016 in “Hypertension research” The authors concluded that utilizing clock gene expression from hair follicle cells may improve circadian-phase estimation in clinical settings, aiding the detection of circadian-related sleep problems despite social time constraints.
38 citations
,
August 2012 in “Biochemical and biophysical research communications” This study found that leukocytes and beard hair follicle cells have an endogenous circadian clock, with PER1 and PER3 expression possibly serving as biomarkers for assessing individual biological clock traits.
12 citations
,
January 2019 in “Sleep medicine” This study found that night shift work disrupts clock gene expression in Japanese men, particularly affecting rhythms and levels of Period3 and Nr1d2, based on the shift schedule.
92 citations
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September 2013 in “Journal of Investigative Dermatology” This study found that peripheral clock genes, particularly BMAL1 and Period1, modulate human hair follicle cycling, suggesting their potential as therapeutic targets for affecting hair growth.
5 citations
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December 2016 in “International journal of biometeorology” In this study, bright light exposure during the daytime did not significantly affect clock gene expression in humans, although Rev-erb-ß expression appeared stronger under bright light compared to dim light.
