The Noggin Null Mouse Phenotype Is Strain Dependent and Haploinsufficiency Leads to Skeletal Defects

    January 2006 in “ Developmental Dynamics
    Przemko Tylżanowski, Liese Mebis, Frank P. Luyten
    Studysummary This research observed that the skeletal abnormalities in Noggin null mice varied based on genetic background, and identified haploinsufficiency leading to joint fusions, similar to human conditions associated with NOGGIN deficiency.
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