Jak Inhibitors: A New Weapon in the Skin Care Providers' Arsenal

    March 2023 in “ PubMed ”
    Osaigbokan Aihie, John A. Dyer
    TLDR JAK inhibitors show promise in treating difficult skin diseases.
    JAK inhibitors, a new class of anti-inflammatory medications targeting the JAK-STAT pathway, showed promise in treating chronic skin diseases that were historically resistant to treatment, such as vitiligo and alopecia areata. They also offered potential benefits for inadequately treated subtypes of atopic dermatitis and psoriasis, as well as genetic conditions like Darier's disease and Hailey-Hailey disease, and inflammatory conditions such as sarcoidosis and localized scleroderma. This review discussed JAK inhibitors approved for dermatologic use and highlighted promising early reports for additional conditions.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 69 results

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      by MagicBold in Research  865 upvotes 1 year ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 2 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community TE turned into Scarring hairloss

      in Update  12 upvotes 2 years ago
      The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

      community Minoxidil can prevent hair follicle miniaturization!?

      in Minoxidil  6 upvotes 4 years ago
      Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hair loss; hair loss could be due to multiple factors, including autoimmune conditions.

    Related Research

    2 / 2 results