Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity

The document discussed the relationship between fat distribution, adipocyte dysfunction, and altered inflammatory markers in patients with polycystic ovary syndrome (PCOS). It highlighted that PCOS, a common endocrine disorder in women of reproductive age, was associated with increased cardiovascular risk and prevalent obesity, particularly visceral adiposity. This obesity was linked to low-grade inflammation and elevated inflammatory cytokines, which were also observed in PCOS patients. The paper explored how these factors interrelated in the context of PCOS.