Hypertension and aldosterone levels in women with early-onset androgenetic alopecia
April 2010
in “British Journal of Dermatology”
TLDR Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
This study found that women with early-onset androgenetic alopecia (AGA) have higher levels of hypertension and aldosterone, which may contribute to the development of AGA. The study recommends blood pressure screening for women with AGA to allow for earlier diagnosis and appropriate treatment. Aldosterone antagonists have been used for a long time for female AGA and may exert a dual beneficial effect in hypertensive patients with AGA, controlling BP and preventing alopecia progression, especially if taken in early stages. However, further studies are needed to confirm these findings.
View this study on academic.oup.com →
Cited in this study
research Elevated aldosterone levels in patients with androgenetic alopecia
Higher aldosterone levels link to hair loss and high blood pressure.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Androgenetic alopecia and coronary artery disease in women
Women under 55 with hair loss (AGA) may have a higher risk of heart disease (CAD).
research Established risk factors for coronary heart disease are unrelated to androgen-induced baldness in female-to-male transsexuals
Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
research Hair Loss, Insulin Resistance, and Heredity in Middle-aged Women. a Population-based Study
Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study
Early balding linked to higher heart disease risk.