Identification of Hydroxylated and Glucuronidated Metabolites of Finasteride in Human Bile and Urine

The study identified hydroxylated and glucuronidated metabolites of finasteride in human bile and urine, providing insights into the drug's metabolic pathways. The research highlighted the presence of these metabolites, which were previously unreported, suggesting that finasteride underwent extensive metabolism in the human body. This finding contributed to a better understanding of the drug's pharmacokinetics and potential implications for its efficacy and safety in treating conditions like androgenetic alopecia and benign prostatic hyperplasia. The study did not specify the number of participants involved.