Hormones and Hair Growth: Variations in Androgen Receptor Content of Dermal papilla Cells Cultured from Human and Red Deer (Cervus Elaphus) Hair Follicles.
TLDR Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.
The document from July 1, 1993, investigated the role of androgens in hair growth by examining androgen receptor content in dermal papilla cells from human and red deer hair follicles. It was found that all human papilla cells had specific androgen receptors, with higher levels in cells from androgen-dependent follicles, such as beard hair, compared to non-balding scalp cells. In red deer, androgen receptors were only detected in cells from mane follicles and not in cells from flank or spring neck follicles. These findings support the hypothesis that androgens influence hair follicles through the dermal papilla and suggest that dermal papilla cells could be useful models for studying androgen action on hair growth. The study highlighted the red deer as a particularly interesting subject due to its shorter hair-growth cycle compared to human hair follicles.
View this study on blackwell-synergy.com →
Cited in this study
research Inductive Properties of Hair Follicle Cells
Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
research 8 Hair follicles and associated glands as androgen targets
Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
research The hair cycle on the human thigh and upper arm
Men's thigh hair grows longer and has a longer growth cycle than women's, but arm hair growth is similar between genders.
research HAIR DIAMETER IN FEMALE BALDNESS
Women with thinning hair have thinner hair strands than women without hair loss.
research HAIR LOSS IN WOMEN
Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
Related
research Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Relation between dermal papilla cells and androgenetic alopecia
research Alopecia
Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
research The Hair Follicle: A Paradoxical Androgen Target Organ
Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
research Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp
Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
research Quantitative study of the human hair follicle in normal scalp and androgenetic alopecia
Alopecia causes smaller hair follicles and affects growth-related structures.
research Hormones and Hair Growth: Variations in Androgen Receptor Content of Dermal papilla Cells Cultured from Human and Red Deer (Cervus Elaphus) Hair Follicles.
Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.
research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.