The History of Hair Transplantation

    December 2008 in “ The American Journal of Cosmetic Surgery ”
    Jae P. Pak, Paulo Gazoni, Alvaro Zeballos, William R. Rassman
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    TLDR Hair transplantation has evolved to refined techniques like FUE and FUT, with Finasteride and Minoxidil as the only other proven treatments for hair loss.
    The document traces the history of hair transplantation from the first case of auto transplantation in 1822 to the advanced techniques of the early 21st century. It notes key developments such as Dr. Orentreich's concept of "donor dominance" in 1959, the Norwood classification for male pattern hair loss in 1975, and the definition of a follicular unit by Dr. Headington in 1984. The evolution of hair transplantation has led to the current use of follicular unit transplantation (FUT) and follicular unit extraction (FUE), with the latter avoiding the scars associated with strip harvesting. Medical treatments like Minoxidil and Finasteride are FDA-approved but have limitations. The document acknowledges that while hair loss affects 50% of men globally, the only proven treatments are Propecia (Finasteride), Rogaine (Minoxidil), and hair transplantation, with FUE and FUT being the most refined techniques available.
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      community Planning to for Hair transplant

      in Transplants  104 upvotes 8 months ago
      The conversation is about someone considering a hair transplant due to ineffective hair loss treatments, with suggestions ranging from trying a hairpiece to continuing with medications like finasteride and minoxidil, and waiting for new treatments. Some advise against a transplant due to the extent of hair loss and the cost, while others share different views on the effectiveness of transplants and non-surgical options.

      community Han Bio Planning Hair Multiplication Trial This Year?

      in Technology  6 upvotes 3 years ago
      Han Bio plans to start clinical trials for a new hair multiplication technology this year, which could significantly reduce the cost and time of hair transplantation. The technology uses a single hair strand to cultivate enough cells for 30,000 hair strands.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

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