Histopathologic Features of Erythematous Papulopustular Eruption to Epidermal Growth Factor Receptor Inhibitors in Cancer Patients

    October 2015 in “ Journal of Cutaneous Pathology ”
    Veronica Bellini, Leonardo Bianchi, Simona Pelliccia, Paolo Lisi
    Studysummary This study found that histopathologic features of erythematous papulopustular eruption due to EGFR inhibitors vary with eruption severity and differ between cetuximab and erlotinib treatments.
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    Research cited in this study 4

    1. Follicular and Epidermal Alterations in Patients Treated with ZD1839 (Iressa), an Inhibitor of the Epidermal Growth Factor Receptor British journal of dermatology/British journal of dermatology, Supplement · 2002
    2. Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin Journal of Investigative Dermatology · 1990
    3. Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages Journal of Investigative Dermatology · 1984
    4. Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle Journal of Investigative Dermatology · 1984