Diagnostic Value of High-Frequency Ultrasound in Evaluation of Subcutaneous Lesions

    September 2023 in “ Skin Research and Technology
    Yao Miao, Weiwei Ren, Fei‐Yue Yang, Liang Li, Lingling Wu, Dan‐ Dan Shan, Zi‐Tong Chen, Li‐Fan Wang, Qiao Wang, Le‐Hang Guo
    TLDR High-frequency ultrasound improves diagnosis accuracy for most subcutaneous lesions.
    The study assessed the diagnostic value of high-frequency ultrasound (HFUS) in evaluating subcutaneous lesions in 355 patients with 391 lesions. HFUS significantly improved diagnostic accuracy from 47.3% with clinical examination alone to 85.9% when combined with clinical examination. It was particularly effective for diagnosing conditions like pilomatrixoma and dermatofibrosarcoma protuberans, where clinical diagnosis alone had low accuracy. HFUS notably increased accuracy for epidermoid cysts, lipomas, pilomatrixomas, haemangiomas, and dermatofibrosarcoma protuberans, though it was less effective for dermatofibromas, neurofibromas, and leiomyomas. The study concludes that HFUS is a valuable tool for enhancing diagnostic accuracy of subcutaneous lesions, especially for benign conditions, but further research is needed to evaluate its effectiveness in distinguishing between benign and malignant lesions.
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