Hair Stimulation with Pulsed Electric Fields

September 2015 in “ Plastic and reconstructive surgery/PSEF CD journals ”

Saiqa Khan, Alexander Golberg, Michael C. McCormack, Marianna Bei, Martin L. Yarmush, William G. Austen

Pulsed Electric Fields PEF hair follicles telogen phase anagen phase hair growth Sprague Dawley rats

Studysummary Low-dose pulsed electric fields in a rat model shifted hair follicles from resting to active growth, with voltage as the most influential factor.

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The study investigated the use of Pulsed Electric Fields (PEF) to stimulate hair growth by shifting hair follicles from the resting telogen phase to the active anagen phase. Using Sprague Dawley rats, the researchers tested various PEF parameters and found that the optimal treatment (270V, 300 pulses, 270us pulse length) resulted in a 5.05-fold increase in anagen follicles compared to controls. Treated sites showed 45.55% of follicles in anagen versus 9.02% in controls (p=0.0008). Voltage was identified as the most influential parameter. The findings suggested that low-dose PEF could effectively stimulate hair growth, warranting further studies on the duration of results, multiple treatments, and mechanisms of action.

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