Hair Protein Glycation as a Long-Term Index of Blood Glucose in Diabetics

    October 1988 in “ Diabetes Research and Clinical Practice ”
    Munetada Oimomi, Naoya Igaki, Shōgo Masuda, F Hata, Yuichiro Maéda, Shinichiro Matsumoto, Shigeaki Baba
    TLDR Hair glycation can indicate long-term blood sugar trends in diabetics.
    The study investigated the use of furosine, a glycation product, to measure hair protein glycation in diabetic patients as an indicator of long-term blood glucose levels. Hair samples, representing approximately 1 year of growth, showed poor correlation with fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) levels at the time of sampling. However, better correlations were found with the year-long average values of FPG, HbA1c, and conduction velocities in two peripheral nerves. This suggested that hair glycation could reflect long-term blood glucose trends and potentially indicate the relationship between diabetic complications and blood glucose levels.
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