Hair Loss

August 2026 in “ JAAPA ”

Clay W. Walker, Daniel Champigny, Thomas Hartman, Brittney Hulsey, Cambrei Hoffart

alopecia telogen effluvium alopecia areata androgenetic alopecia thyroid-stimulating hormone scalp biopsy intralesional steroids baricitinib minoxidil antifungals tinea capitis trichoscopy hair loss Rogaine

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Baricitinib →

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary This article provides physician associates with an evidence-based approach to diagnosing and treating alopecia, focusing on recognizing patterns, identifying triggers, and applying targeted interventions to improve patient outcomes in hair loss.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

15 / 15 results

research Frontal Fibrosing Alopecia in Men: A Review of the Literature

March 2025 in “Journal of Clinical Medicine”

This review discusses the unique clinical features, challenges in diagnosis, and treatment protocols of frontal fibrosing alopecia in men, noting the overlap with other types of alopecia and the need for further studies.

research Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss

November 2024 in “JAMA Dermatology”

This consensus statement provides expert guidance on prescribing low-dose oral minoxidil for hair loss, noting a lack of representation of pediatric specialists and highlighting areas for future research.

research Low-Level Laser And LED Therapy In Alopecia: A Systematic Review And Meta-Analysis

October 2024 in “Dermatologic Surgery”

In this study, low-level laser/LED therapy significantly increased hair density in patients with androgenetic alopecia compared to placebo over 4 to 26 weeks; however, the efficacy for other alopecia types remains unclear, requiring further research.

research Dupilumab Induces Hair Regrowth in Pediatric Alopecia Areata: A Real-World, Single-Center Observational Study

20 citations , July 2024 in “Archives of Dermatological Research”

This study observed that dupilumab led to significant hair regrowth and was well-tolerated in children with both alopecia areata and atopic dermatitis, showing promise as a safe treatment option for pediatric patients with associated atopy.

research Approach to the Patient With Hair Loss

1 citations , August 2023 in “Journal of the American Academy of Dermatology”

This continuing medical education article outlines the comprehensive approach needed to diagnose alopecia, emphasizing the importance of a thorough history, scalp and hair examination, and, if necessary, laboratory analysis and biopsy for effective treatment planning.

research Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss

11 citations , November 2022 in “JAMA dermatology”

This review suggests that certain nutritional supplements may have a potential role in improving hair loss, though evidence quality varies, and such treatments should be discussed collaboratively between physicians and patients.

research Male and Female Pattern Hair Loss: Treatable and Worth Treating

11 citations , March 2021 in “Cleveland Clinic Journal of Medicine”

In this overview, the authors note that both pharmacologic and nonpharmacologic treatments are effective for pattern hair loss, emphasizing early detection and intervention to maintain hair.

research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee

49 citations , February 2019 in “The Journal of Clinical Endocrinology and Metabolism”

This review offers evidence-based recommendations for diagnosing and treating female pattern hair loss, emphasizing clinical assessment and starting treatment with minoxidil, while noting that measurement of certain hormones and vitamins is optional.

The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis

38 citations , February 2019 in “Clinical Interventions in Aging”

This meta-analysis found that dutasteride was more effective than finasteride in increasing hair count and improving photographic assessments for men with androgenetic alopecia, while both drugs had similar rates of sexual dysfunction-related adverse effects.

Severe Hair Loss Associated with Psychotropic Drugs in Psychiatric Inpatients—Data from an Observational Pharmacovigilance Program in German-Speaking Countries

research Severe Hair Loss Associated with Psychotropic Drugs in Psychiatric Inpatients—Data from an Observational Pharmacovigilance Program in German-Speaking Countries

5 citations , August 2018 in “European Psychiatry”

In this large multicenter study, severe hair loss related to psychotropic drug treatment was very rare but occurred more frequently in female patients, with valproic acid showing the highest risk.

research Evaluation and Diagnosis of the Hair Loss Patient

86 citations , August 2014 in “Journal of The American Academy of Dermatology”

This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.

research Drugs and Hair Loss: Mechanisms and Clinical Implications

54 citations , September 2012 in “Dermatologic Clinics”

This review discusses possible medication-induced hair loss and the need to exclude other confounding factors like stress and illness; it reports no new clinical findings and emphasizes careful assessment before attributing hair loss to medications.

research Alopecia Areata: An Autoimmune Disease Causing Hair Loss

421 citations , April 2012 in “The New England Journal of Medicine”

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

research Hair Loss in Psychopharmacology

63 citations , March 2000 in “Annals of clinical psychiatry”

This article reviews the association between psychopharmaceuticals and medication-induced alopecia, noting that hair regrowth typically occurs after discontinuing or reducing the medication, while mineral supplements' effectiveness remains unclear.

research Alopecia and Mood Stabilizer Therapy

38 citations , September 1996 in “Annals of Clinical Psychiatry”

This review discusses the association between mood stabilizers and alopecia, providing diagnosis insights and management options, but reports no new clinical results.