Age-Induced Hair Graying and Oxidative Stress

September 2016 in “ Springer eBooks ”

Miri Seiberg

oxidative stress hydrogen peroxide H2O2 melanocytes catalase proteins antioxidants

TLDR Gray hair is caused by oxidative stress damaging hair cells.

The document discussed age-induced hair graying, emphasizing oxidative stress's role in this process. It highlighted that oxidative stress, particularly hydrogen peroxide (H2O2) accumulation, damaged melanocytes, leading to gray hair. Reduced catalase activity, which breaks down H2O2, contributed to this damage. The document also referenced studies on the protective roles of proteins and antioxidants in mitigating oxidative stress, with potential implications for preventing or reversing hair graying.

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Research cited in this study

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