Corn Silk Extract Improves Benign Prostatic Hyperplasia in Experimental Rat Model

January 2017 in “ Nutrition Research and Practice ”

So Ra Kim, Ae Wha Ha, Hyun Ji Choi, Sun Lim Kim, Hyeon Jung Kang, Myung Hwan Kim, Woo Kyoung Kim

corn silk extract benign prostatic hyperplasia testosterone 5α-reductase type 2 dihydrotestosterone prostate-specific antigen BPH 5α-R2 DHT PSA

Studysummary In this study, corn silk extract treatment improved symptoms of testosterone-induced BPH by reducing specific mRNA expression and decreasing levels of 5α-R2, DHT, and PSA.

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In the study titled "Corn silk extract improves benign prostatic hyperplasia in experimental rat model," benign prostatic hyperplasia (BPH) was induced in rats through testosterone injections. The treatment with corn silk extract was found to improve BPH symptoms by inhibiting the mRNA expression of 5α-reductase type 2 (5α-R2) and reducing the levels of 5α-R2, dihydrotestosterone (DHT), and prostate-specific antigen (PSA) in both serum and prostate tissue.

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