Pathogenesis of Genetic Human Hair Disorders

    August 1981 in “ The Journal of Dermatology
    Takashi Aoyagi, Yusho Miura, Paul S. Porter
    TLDR All major hair defects involve cuticle abnormalities.
    The document discussed various congenital hair disorders, focusing on morphological abnormalities such as defective cuticle formation and reduced sulfur content. These abnormalities were primarily related to structural defects in the cuticle, cortex, and medulla of the hair. The studies highlighted that cuticle defects were present in every case of major structural hair defects examined.
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