Feline And Canine Cutaneous Lymphocytosis: Reactive Process Or Indolent Neoplastic Disease?
January 2022
in “
Veterinary Sciences
”
TLDR Feline cutaneous lymphocytosis is likely reactive, while canine cutaneous lymphocytosis needs more study to understand its nature.
The study examined cutaneous lymphocytosis (CL) in 19 cats and 10 dogs, focusing on its clinical, histological, and immunohistochemical characteristics. In both species, common symptoms included alopecia, erythema, and scales, with a dermal infiltrate of lymphocytes observed histologically. In cats, the infiltrate was consistently CD3+ and polyclonal, suggesting a reactive nature and associated with prolonged survival (median 1080 days). In dogs, the infiltrate was more heterogeneous, with both CD3+ and CD20+ lymphocytes and clonal rearrangements, indicating a more complex condition with variable clinical outcomes. The findings suggested that feline CL was likely reactive, while canine CL required further investigation to distinguish it from epitheliotropic lymphoma (CEL).
