37 citations
,
November 1995 in “Journal of Investigative Dermatology” This study found that topical finasteride and flutamide both significantly reduced sebaceous gland growth and decreased prostatic weights in hamsters, indicating systemic effects despite local application.
40 citations
,
January 1994 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone affect human sebocytes differently depending on the skin region, with spironolactone inhibiting their proliferation and counteracting androgen effects in facial sebocytes.
9 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the in vitro growth of hair follicle cells, particularly papilla cells and outer root sheath keratinocytes, is influenced by different concentrations of androgens and antiandrogens.
12 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that hair follicle cells' growth in vitro is influenced by the concentration of androgens and antiandrogens, with papilla cells and outer root sheath keratinocytes showing distinct sensitivity.
9 citations
,
October 1991 in “Archives of Dermatological Research” Testosterone, DHT, and estradiol significantly affect hair cell growth.
12 citations
,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
69 citations
,
August 1988 in “Journal of Investigative Dermatology” 15 citations
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June 1986 in “Pediatric Dermatology” This study observed that 5α‐dihydrotestosterone increased pigmentation in certain skin areas of male Syrian hamsters, while estradiol decreased melanocyte numbers and counteracted the androgen-induced pigmentation effects.
25 citations
,
November 1979 in “International Journal of Dermatology” This article reviews the metabolism and action of androgen in the skin but reports no new experimental results; the author calls for further research.