October 2022 in “Dermatologic Therapy” This study found no significant difference in the overall effectiveness of fractional CO2 laser plus triamcinolone acetonide versus microneedling plus the same treatment for resistant alopecia areata, though initial hair regrowth appeared more frequently in the laser group.
October 2022 in “Dermatology practical & conceptual” This study found that micro-needling with triamcinolone acetonide led to the best treatment outcomes for alopecia areata compared to other methods of trans-epidermal drug delivery.
January 2026 in “Ciencia Latina Revista Científica Multidisciplinar” This study reports on a 14-year-old male with refractory diffuse alopecia areata who achieved full hair density restoration after three monthly sessions of microneedling combined with triamcinolone, dutasteride, and synthetic exosome treatment, highlighting exosomes' potential for enhancing traditional therapies in autoimmune hair loss cases.
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January 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study found that treating patchy alopecia areata with fractional CO2 laser and topical triamcinolone acetonide was more effective and safer than intralesional triamcinolone, despite higher initial discomfort, as it resulted in greater patient satisfaction and fewer adverse effects like skin atrophy.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a new triamcinolone acetonide serum combined with a microneedling device, showing promise for treating alopecia areata by targeting hair follicles in a less invasive, patient-friendly way with confirmed drug solubility, compatibility, and safety.