Alopecia Areata Treated Using CO2 Fractional Laser With Different Parameters

January 2025 in “ Lasers in Medical Science ”

Shu Nie, Zezhi He, H.M. Shen, Runxiang Li, Huilan Zhu

alopecia areata CO2 fractional laser tofacitinib oral prednisone compound Siyadan ointment AA CO2 laser prednisone

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Tofacitinib →

a JAK inhibitor for alopecia areata and other autoimmune conditions

Studysummary In this reported case, a 13-year-old boy with alopecia areata experienced complete lesion resolution and varied hair regrowth across different laser treatment parameters after three months of combined oral prednisone, topical ointment, and CO2 fractional laser therapy.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This case study explores the use of CO2 fractional laser treatment with varying parameters on a 13-year-old male with alopecia areata (AA). The patient, who had previously experienced suboptimal results with tofacitinib, was treated with oral prednisone, compound Siyadan ointment, and CO2 fractional laser therapy. The laser treatment was applied to nine different areas with varying energy and depth settings, while one area was left untreated as a control. After three months, the patient's lesions fully resolved, with hair growth observed in all treated areas, including the control. The study highlights the potential of CO2 fractional laser in treating AA, though it emphasizes the need for further research to establish optimal treatment parameters.

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Research cited in this study

3 / 3 results

Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study

research Evaluation of Fractional Carbon Dioxide Laser Alone Versus Its Combination With Betamethasone Valerate in Treatment of Alopecia Areata: A Clinical and Dermoscopic Study

3 citations , September 2022 in “Archives of dermatological research”

In this study, fractional CO2 laser treatment for alopecia areata was found to significantly increase terminal hair and patient satisfaction compared to betamethasone valerate cream alone, highlighting its efficacy and safety both as a standalone and combined treatment.

research Comparative Study Between Fractional Carbon Dioxide Laser vs Intralesional Steroid Injection in Treatment of Alopecia Areata

18 citations , June 2020 in “Dermatologic Therapy”

In this study, FCO2 laser treatment showed significantly better improvement for alopecia areata compared to traditional intralesional corticosteroid injections, with no serious side effects or relapse observed.

research Effects of CO2 Fractional Laser on Hair Growth in C57BL/6 Mice and Potential Underlying Mechanisms

3 citations , March 2019 in “Chinese Medical Journal”

In this study using mice, fractional CO2 laser therapy promoted hair regrowth by inducing moderate inflammation, enhancing VEGF-mediated angiogenesis, and activating the Wnt10b signaling pathway.