Understanding Eyebrow and Eyelash Involvement in Patients with Alopecia Areata and Responsiveness to Treatment with Baricitinib

    April 2025 in “ PubMed
    Arash Mostaghimi, Brittany G. Craiglow, Brett King, Jerry Shapiro, Justin Ko, Antonellá Tosti, Manabu Ohyama, Yiying Brogan, Guanglei Yu, Angelina Sontag, Najwa Somani
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Baricitinib →

    JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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    Studysummary In these randomized, placebo-controlled trials, patients with alopecia areata who received baricitinib showed significantly higher eyebrow and eyelash hair regrowth rates compared to placebo, with greater responses observed at the 4 mg dose and in those achieving overall scalp hair improvement by Week 52.
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