Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.
November 1995
in “
The EMBO Journal
”
Research cited in this study
10 / 10 resultsresearch Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development
FGF and EGF are crucial for hair follicle development and growth.
research Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation
TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
research The Secret Life of the Hair Follicle
Hair follicles create different cell layers and proteins, controlled by various molecules.
research Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.
TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.
research Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination
research Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin
research Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages
research Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle
research Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth
research Epidermal growth factor delays the development of the epidermis and hair follicles of mice during growth of the first coat
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