Evidence Based Hair Restoration: Designing Clinical Trials

May 2006 in “ Hair transplant forum international ”

Andreas Finner, Berthold Rzany, Jerry Shapiro

hair transplantation evidence-based medicine clinical trials hair growth assessment standardized protocols objective measurement tools International Society of Hair Restoration Surgery hair transplant EBM ISHRS

TLDR Well-designed clinical trials are needed to improve hair restoration methods.

The document discussed the application of Evidence-Based Medicine (EBM) in hair transplantation (HT). It highlighted the importance of designing robust clinical trials to improve the quality of evidence in HT. Specific challenges in conducting these studies were identified, such as variability in patient characteristics and the subjective nature of hair growth assessment. The authors proposed solutions like standardized protocols and objective measurement tools. The role of the International Society of Hair Restoration Surgery (ISHRS) in promoting high-quality research was emphasized. The conclusion stressed the need for well-designed clinical trials to advance the field of hair restoration.

View this study on ishrs-htforum.org →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Effects of Finasteride (1 mg) on Hair Transplant

30 citations , March 2006 in “Dermatologic Surgery”

Finasteride improves surrounding scalp hair and increases hair density after hair transplant.

research Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss

86 citations , February 2003 in “Journal of The American Academy of Dermatology”

New methods improve how we test hair growth treatments, but challenges like slow hair changes and high costs remain.

Related Community Posts Join

6 / 1000+ results

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 3 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Verteporfin and Microneedling

in Treatments 1 year ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community The end of balding: We may have just found the secret to hair regrowth

in Technology 676 upvotes 8 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.

community 2022 Official beginner guide for "I'm losing my hair, what can I do?"

in STARTER GUIDE 686 upvotes 3 years ago

Hair loss treatments include Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. Additional options are Dutasteride, oral Minoxidil, and hair transplants.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 3 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

Similar Research

5 / 1000+ results

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

145 citations , November 2017 in “Journal of The European Academy of Dermatology and Venereology”

Use minoxidil for hair loss treatment; assess results after 6 months.

A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia

research A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia

25 citations , May 2020 in “Stem Cells Translational Medicine”

ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.

research Training Requirements and Recommendations for the Specialty of Dermatology and Venereology: European Standards of Postgraduate Medical Specialist Training

10 citations , June 2019 in “Journal of the European Academy of Dermatology and Venereology”

The document emphasizes standardized, comprehensive training for dermatology and venereology specialists across Europe.

research Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review

41 citations , December 2017 in “Lasers in Medical Science”

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.