Etiopathogenesis of Acne
February 2006
in “
Expert review of dermatology
”
TLDR Acne is caused by hormones, genetics, skin cell buildup, oil production, bacteria, and inflammation.
Acne was identified as a chronic hormonal–genetic disorder with a complex genetic basis and varied transmission patterns. Key factors in its development included hyperkeratinization of the upper hair follicle, increased sebaceous production, bacterial colonization of follicles, and inflammation in and around the follicles. The paper reviewed these etiopathogenetic factors comprehensively.