Exploring the Function of Epicardial Cells Beyond the Surface

This article discusses advancements in heart tissue engineering, emphasizing the importance of environmental signals for cardiomyocyte survival and growth, but reports no new clinical findings.

This study found that induced pluripotent stem cells derived from human keratinocytes efficiently differentiated into cardiomyocytes, forming a homogeneous population with cardiac-specific molecular and functional properties, and demonstrated significant cardiac marker expression and spontaneous contraction capabilities over 15 days of differentiation induction.

This study found that a pro-fibrotic Wnt1/βcatenin injury response is crucial for maintaining cardiac function following acute ischaemic cardiac injury by activating the epicardium and cardiac fibroblasts.

This study found that treating skin wounds with a combination of epidermis-derived epithelial-like stem/progenitor cells and platelet-rich plasma improved tissue repair and increased vascularization and elastin content compared to platelet-rich plasma alone.

This review examines the role of epidermal stem cells in wound healing, discussing their characteristics and mechanisms, but does not report new clinical results.