Efficacy of Intradermal Minoxidil 5% Injections for Treatment of Patchy Non-Severe Alopecia Areata

July 2020 in “ Journal of Dermatological Treatment ”

Mahmoud M. S. Abdallah, Rasha Shareef, Marwa Yassin Soltan

minoxidil intradermal minoxidil alopecia areata triamcinolone acetonide micro-needling corticosteroid treatment Rogaine steroids

From the encyclopedia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Triamcinolone Acetonide →

Studysummary This study found that intralesional minoxidil alone has limited efficacy for non-severe patchy alopecia areata, though it may accelerate hair regrowth compared to spontaneous recovery. Our plain-language summary of this paper — not a Tressless recommendation.

In 2020, Mahmoud Abd El-Rahim Abdallah, Rasha Shareef & Marwa Y. Soltan conducted a study involving 20 patients with 100 patches of non-severe alopecia areata (AA). They tested the efficacy of intradermal minoxidil 5% injections, intralesional triamcinolone acetonide, a combination of both, and micro-needling. The results indicated that intradermal minoxidil was nearly as effective as micro-needling and its combination with steroids did not enhance the effect. However, hair regrowth due to minoxidil occurred earlier than spontaneous recovery. The study concluded that while minoxidil alone had limited efficacy in treating non-severe patchy AA, it could speed up the recovery process. The study did not support the use of minoxidil in combination with steroids for patchy non-severe AA. Less invasive methods like intralesional minoxidil or micro-needling were suggested for patients who refuse or have contraindications to standard corticosteroid treatment.

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Research cited in this study

12 / 12 results

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research Alopecia Areata: Overview and Insights from January 2018

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research Scalp Roller Therapy in Resistant Alopecia Areata

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research Hair Shafts in Trichoscopy

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research A Study to Evaluate the Efficacy of Various Topical Treatment Modalities for Alopecia Areata

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research Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration

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research Immunohistochemical Characterization of the Cellular Infiltrate in Severe Alopecia Areata Before and After Minoxidil Treatment

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