Commentary on: The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma in Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB Study

June 2021 in “ Aesthetic Surgery Journal ”

Jack C. Fisher

platelet-rich plasma PRP hair density hair diameter androgenetic alopecia AGA saline control platelet concentration hair loss hair thickness male pattern baldness

TLDR PRP improves hair growth in AGA, but higher concentrations aren't significantly better than lower ones.

The study investigated the effects of different concentrations of platelet-rich plasma (PRP) on hair density and diameter in androgenetic alopecia (AGA) through a randomized, double-blinded, placebo-controlled, parallel-group design involving 8 patients. The results indicated that PRP, regardless of concentration, had a positive effect on hair compared to saline control. However, the difference between higher and lower concentrations of PRP was not significant, though higher doses showed a slightly better clinical outcome. The study emphasized the importance of early treatment and patient selection for PRP efficacy in hair loss management. Further research is needed to determine the optimal platelet concentration for clinical effects.

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