Research Paper: Effects of Fructus Ligustri Lucidi Water Extract on Proliferation and Intracellular Signaling of Dermal Papilla Cells

    January 2011 in “ 한국미용학회지 ”
    임난영, 김대성, 우원홍, 문연자, 고경숙
    TLDR Fructus Ligustri Lucidi water extract may help hair growth by promoting cell survival.
    The study investigated the effects of Fructus Ligustri Lucidi water extract (FLLW) on human hair dermal papilla cells (HHDPc). Using MTT assays and Western blot analysis, it was found that FLLW and minoxidil significantly increased HHDPc proliferation. Specifically, FLLW at 10 μg/mL increased ERK phosphorylation by 234% and Akt phosphorylation by 120%, while minoxidil at 0.1 μM increased ERK phosphorylation by 188% and Akt phosphorylation by 119%. The conclusion was that FLLW promotes HHDPc survival by activating ERK and Akt pathways, suggesting it could stimulate hair growth by extending the anagen phase.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 19 results

      community L'Oréal Serioxyl Vs Garnier fructus stemoxydine

      in Product  6 upvotes 2 years ago
      L'Oreal Serioxyl and Garnier Fructus Stemoxydine are compared for effectiveness in hair loss treatment. The user considers switching from Serioxyl to the cheaper Garnier Fructus but is unsure about its effectiveness and stemoxydine percentage.

      community Can I expect regrowth on a low dose of fin?

      in Treatment  19 upvotes 2 years ago
      A user's experience with hair loss and their consideration of using finasteride, minoxidil, RU58841, stemoxydine, fluridil, and peptide serum with redensyl as treatment options.

      community Shampoo for dry and itchy scalp

      in Product  3 upvotes 3 years ago
      A user shared that Garnier Fructis SOS repair shampoo with amla oil and liquid vegetal keratin helped with their dry and itchy scalp. They have been using finasteride and minoxidil for a year and found this shampoo effective after trying many others.

      community Creating an all-in one topical. Dumb idea?

      in Treatment 2 years ago
      The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.

    Similar Research

    5 / 109 results