Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride

    November 2014 in “International Journal of Dermatology
    Jae-Yoon Jung, Je Young Yeon, Jee Ho Choi, Soon Young Kwon, Beom Joon Kim, Sang Woong Youn, Kyoung Un Park, Chang Hun Huh
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    TLDR Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
    The study found that dutasteride at a dose of 0.5 mg/d could be an alternative therapeutic option for patients with androgenetic alopecia (AGA) who did not respond to finasteride. Hair density and thickness significantly increased by 10.3% and 18.9%, respectively, in phototrichogram assessment. However, the incidence of dutasteride-related sexual dysfunction is reported to be higher than with finasteride, so further research is required to identify the incidence of dutasteride-related sexual dysfunction and the timing to switch to dutasteride if there was no clinical improvement.
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