Editorial: Application of Mesenchymal Stem Cells and Their Secretory Factors for Hair Regeneration
September 2017
in “
Current stem cell research & therapy
”
mesenchymal stem cells MSCs adipose tissue ADSCs secretory factors ADSC-conditioned media ADSC-CM follicular cell cycles hair cycles androgenetic alopecia telogen effluvium hair regeneration novel delivery platforms alopecia scalp health hair regrowth stem cells fat tissue conditioned media hair loss hair growth
TLDR Mesenchymal stem cells from fat tissue may effectively treat hair loss and help regrow hair.
The editorial from 2017 discusses the potential of mesenchymal stem cells (MSCs), particularly those from adipose tissue (ADSCs), and their secretory factors in promoting hair growth and regeneration. It highlights recent findings that ADSCs and ADSC-conditioned media (ADSC-CM) can modulate follicular cell cycles and hair cycles both in vitro and in vivo, offering promising treatments for hair loss disorders such as androgenetic alopecia and telogen effluvium. The issue includes discussions on the basic mechanisms of hair regeneration by MSCs, the use of novel delivery platforms to enhance therapeutic responses, and the application of ADSC-CM as a new therapy for alopecia. The articles in this special issue aim to bridge stem cell biology with clinical practice and suggest that ADSC-CM is an effective, safe, and convenient therapy for hair loss, with minimal rebound effect and the potential to improve scalp health and facilitate hair regrowth.
