Dutasteride Infusion in Male Androgenetic Alopecia Using a Novel Drug Delivery Technique: MMP

    July 2025 in “ Skin Appendage Disorders ”
    Luciana Gasques, Alice Marques Moreira Lima, Mariana Lima, Antonellá Tosti, Márcio Luís Andrade e Silva, Marina Barletta
    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    Studysummary In this study, researchers found that microinfusion of dutasteride using the MMP® technique did not show a statistical difference compared to placebo in clinical assessments for male androgenetic alopecia, though patients reported improvements in the vertex area.
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    The study investigated the efficacy and safety of using the MMP® technique for microinfusion of dutasteride compared to a saline placebo in treating male androgenetic alopecia (AGA). Conducted on 8 adult male patients, the trial involved three monthly applications. While no statistical difference was observed in clinical assessments between the groups, patients reported significant improvement in the vertex area with dutasteride. The study concludes that dutasteride microinfusion using MMP® is effective for male AGA, and microneedling with MMP® alone also shows effectiveness.
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