Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation

    March 2021 in “ Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ”
    Jiro Kishimoto, Yumiko Ishimatsu‐Tsuji
    TLDR Fat tissue around hair follicles releases a growth factor that helps hair grow and develop color.
    The study by Nicu C et al. demonstrated that dermal white adipose tissue (dWAT) surrounding hair follicles (HFs) plays a crucial role in regulating human hair growth and pigmentation through HGF/c-Met signaling. This finding suggested that targeting HGF/c-Met signaling in the perifollicular region could offer a novel therapeutic approach for treating disorders related to human hair growth and pigmentation.
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