Delaying Treatment in Male-Pattern Hair Loss Affects the Therapeutic Response

This article discusses the effects of delaying treatment for male-pattern hair loss (MPHL) on the therapeutic response. The authors report a case of monozygotic twins in which one twin delayed treatment for 12 months, resulting in a marked difference in hair regrowth compared to the other twin who started treatment immediately. The authors suggest that future MPHL studies should use an active rather than a placebo/untreated control, as previous studies have shown that men enrolled in the placebo or untreated arm continue to lose hair. The article also briefly discusses the association between isotretinoin treatment for acne and elevated homocysteine levels, which may be a reason for the development of psychiatric problems.