Comparison of Complications of Non-Resorbable (Permanent) Fillers and Resorbable Fillers

    September 2024 in “ Journal of Cosmetic Dermatology
    Tom S. Decates, Valerie Vroege, Merel A. Hamer, Peter J. Velthuis
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    Studysummary In this study, researchers observed that complications from non-resorbable fillers have decreased, whereas those from resorbable hyaluronic acid fillers have increased in recent years, with non-resorbable fillers still being the most common cause of complications.
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    The study compares complications from non-resorbable (permanent) and resorbable fillers at the Erasmus Medical Centre in the Netherlands. Between 2011 and 2016, 77.6% of complications were due to permanent fillers, but this decreased to 50.6% in 2022. The study included 316 patients in 2022, with 160 complications from non-resorbable fillers and 131 from hyaluronic acid fillers. Despite a ban on permanent fillers in the Netherlands since 2015, complications persist due to delayed onset and treatments abroad. Permanent fillers often cause long-term issues like inflammation and scarring, posing significant physical, psychological, and financial burdens. More studies are needed to better understand these complications and inform both patients and healthcare providers.
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