Combination Treatment With Methotrexate for Severe Alopecia Areata

A case study from the Philippines documents the successful treatment of severe diffuse alopecia areata (AA) in a 20-year-old female using a combination of corticosteroids and methotrexate, resulting in significant hair regrowth from a Severity of Alopecia Tool score of 92% to 0.1% after 6 months. This highlights the efficacy and affordability of traditional therapies in regions with limited access to advanced treatments, emphasizing the importance of tailored treatment approaches and continued research into optimal strategies for managing AA.