Clinico-Laboratory and Trichoscopic Evaluation of Various Patterns of Female Baldness: A Prospective Case-Control Study

March 2021 in “ IP Indian journal of clinical and experimental dermatology ”

Sappa Ramatulasi, Manjari Annapurna Malladi, Ruttala Sri Satya, Kashetty Srujan Kumar, Anand Acharya

female pattern hair loss FPHL total testosterone DHEAS TSH serum ferritin hair diameter diversity peripilar sign female pattern baldness iron deficiency

TLDR Hormones and iron deficiency are linked to female pattern hair loss, and hair thinning patterns are similar across different types of this condition.

The study "Clinico -laboratory and trichoscopic evaluation of various patterns of female baldness – A prospective case control study" conducted by Sappa Ramatulasi et al. in 2019 involved 70 female patients aged 18-48 years with pattern baldness and 30 age-matched females as controls. The study found a significant difference in the mean values of total testosterone, DHEAS, TSH between the cases and controls. Additionally, 52% of the cases had serum ferritin levels less than the cut-off level of 40 mic.gram/L, and the mean serum ferritin values of cases were less than that of controls. The most frequent trichoscopic findings were hair diameter diversity (90%) and peripilar sign (91.4%). The study concluded that hormones and iron deficiency play a role in the etiology of Female Pattern Hair Loss (FPHL), and trichoscopic findings did not significantly differ between the three forms of FPHL.

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