Clinico-Biochemical Characteristics of 229 Portuguese Infertile Women with Polycystic Ovary Syndrome: Clinical Relevance and Relationship with Fertility Treatment Results

    Pedro Marques, Fabiana Ferreira, Ana Paula Soares, Jefferson Torres Nunes, Sara de Sousa, Azevedo Jeremias Aguiar, Carlos Calhaz–Jorge
    TLDR Certain health factors can worsen fertility treatment results in women with PCOS.
    The study examined 229 Portuguese infertile women with polycystic ovary syndrome (PCOS) to identify factors affecting fertility treatment outcomes. It found that primary infertility, a family history of type 2 diabetes mellitus (T2DM), hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, older age, waist circumference greater than 80 cm, and high luteinizing hormone (LH) levels were associated with poorer fertility treatment results. These clinico-biochemical characteristics were considered clinically relevant in understanding and potentially improving fertility treatment strategies for women with PCOS.
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