The Association Between Clinical and Biochemical Hyperandrogenism in Women With Female Pattern Hair Loss

The study evaluated the association between clinical and biochemical hyperandrogenism (HA) in 362 premenopausal women with female pattern hair loss (FPHL). It found that while FPHL severity was associated with clinical signs of HA like hirsutism and acne, it did not correlate with biochemical parameters of HA such as total testosterone, free testosterone, and bioavailable testosterone. The severity of FPHL was not influenced by other factors like SHBG, HOMA-IR, or BMI. The findings suggested that the assessment of FPHL should be primarily clinical, with biochemical tests serving as a diagnostic aid.