Cicatricial Alopecia Due to Hair Coloring Burn

    January 2004 in “ Linchuang pifuke zazhi ”
    Yang-Hyun Yoon, Cho-Wan Ik, Byung-In Roo
    TLDR A man lost hair permanently from a salon burn, and surgery was needed to fix the scar.
    A 24-year-old man developed secondary cicatricial alopecia after a steam cap burn at a hair salon, resulting in a 4x2.5 cm bald patch on his scalp. Initial treatments, including burn dressing and triamcinolone injections, were ineffective. Subsequent treatment with KMNO4 wet dressing, topical antibiotics, and minoxidil solution for 7 months also showed no improvement. A biopsy revealed perifollicular fibrosis and complete absence of follicles. After 13 months, the patient underwent surgical excision and closure of the scar by a plastic surgeon. This case highlighted the rarity of hairdressing-related burns leading to secondary cicatricial alopecia.
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      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 1 month ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

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      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 1 year ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  56 upvotes 8 months ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Can we get a reality check on PP405?

      in Research/Science  76 upvotes 1 month ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

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