Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels

This review examines how chirality affects the formation and properties of peptide-based hydrogels. It explores systems with peptides of all L- or D-amino acids, alternating chirality, and mixtures of L- and D-peptides. The study highlights differences in structural and mechanical properties between homochiral and heterochiral peptide hydrogels. Additionally, it discusses potential biological applications, emphasizing the impact of chirality on the functionality of these hydrogels.