Chemotoxicity in Carcinoma Breast Patients: Its Incidence and Trends in Severity - An Observational Study

The study observed 50 female carcinoma breast patients undergoing chemotherapy to assess the prevalence and severity of chemotoxicities. Hair loss was prevalent in 98% of patients with increasing severity, while nausea and vomiting were experienced by 100% and 54% of patients, respectively, with a decreasing trend in severity. Fatigue was universally experienced with increasing severity, and leukopenia and thrombocytopenia were noted multiple times in several patients. No significant differences in toxicity were found between chemotherapy regimens, and severe chemotoxicity was minimal. The findings suggested that proper patient counseling on these adverse effects could mitigate their impact on quality of life.