The Effects of Botulinum Toxin on Vascular Diameter: A Preliminary Report

This preliminary report examines the effects of botulinum toxin type A (BoNT-A) on vascular diameter in 5 patients, finding that BoNT-A significantly increased the diameter of the supratrochlear artery from 0.87 ± 0.38 mm to 1.69 ± 0.27 mm, while normal saline had no effect. Although arterial velocity decreased post-injection, this was not statistically significant. The results suggest BoNT-A's potential for treating vascular ischemia due to its vasodilatory effects, but the small sample size limits the findings' generalizability. Further research with larger cohorts is needed to confirm these effects and explore its application in other vascular areas.