In Vitro and In Vivo Characterization of Bio-Patch to Hydrogel on Skin Wounds for Efficient Scarless Wound Healing

January 2024 in “ Journal of chemical health risks ”

Divya Sahu, Manisha Chandrakar, Trilok Nath Patel, Lilima Baghel, Deepa Thakur, Ume Kulsum, Jhakeshwar Prasad

aloin arginine alginate hydrogel skin regeneration tissue repair antibacterial properties anti-inflammatory properties cutaneous wound dressing

TLDR The bio-patch promotes faster, scarless wound healing.

The study introduces a multifunctional aloin-arginine-alginate (3A) bio-patch designed to transform into a hydrogel upon absorbing exudate or blood from wounds, aimed at enhancing skin regeneration and tissue repair. The 3A bio-patch features a porous structure, excellent swelling properties, and biodegradability, enabling rapid absorption of wound exudates and conversion into a hydrogel. It also demonstrates significant antibacterial and anti-inflammatory properties, promoting accelerated wound healing and scarless repair in vivo. This innovative approach offers a promising solution for developing effective cutaneous wound dressing materials.

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